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Native IGF-1 is a 70-amino-acid single-chain peptide with structural homology to proinsulin

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By day seven, wounds treated with 1 milligram per milliliter AA4 had closed by 90.7 percent, compared with just 50 percent in untreated diabetic controls, and the 3 milligram per milliliter formulation achieved 95.5 percent closure, outperforming both native asiatic acid and adenosine monophosphate