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COM March 2009 Diagnosis - UW School of Dentistry
Weight loss, weakness, fatigue, heart palpitations, tanning or darkening of the skin, abdominal pain and, especially in the case of hemochromatosis, joint pain are among the complaints that may be observed due to diseases that result in increased ferritin
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As a result, brown or black pigment will appear on the mucosal membranes.28 Some macrophages with abundant pigments may be present in the submucosal layer, submucosal lymphatic vessels and some other parts of the organ.21 In addition, GNG5, LPAR3, MAPK8, and PSMC6 might be candidate biomarkers associated with apoptosis in MC.29 Yamate et al.30 speculated that as the apoptosis of the mucosal epithelium or lamina propria layer is reduced, it could delay the progression of MC