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Therefore, the transfer of acyl moieties from fatty acyl-CoA esters to carnitine also replenishes intracellular free CoA that is crucial for intermediary metabolism [53]
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Further, while dietary l-carnitine supplementation induced no differences in fecal transformation of the first step of the l-carnitine→γBB→TMA/TMAO metaorganismal pathway in either omnivores or vegans/vegetarians, dietary l-carnitine provision induced enhanced fecal microbial transformation of the second microbial step in the overall pathway (i.e., d 9 -γBB→d 9 -TMA) in omnivores ( P = 0.02), but not vegans/vegetarians ( P = 0.69) (Figure 5C)
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