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in very high doses it causes a reddish discoloration of the skin, and also of the urine (chromaturia, which could be mistaken for blood in the urine)

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Acknowledgements This work was supported by the Medical Research Council [grant numbers MR/J01186X/1, G0901321, MR/M006301/1], (the third grant is a UK New Investigator Research Grant supporting MJB)

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