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Additionally, the impaired clearance of β-amyloid due to compromised renal function further contributes to the development of cognitive decline (96)

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Lipid-laden adipocytes produce increased levels of cytokines such as Interleukin 6 (IL-6), IL-β, TNF-α, monocyte chemoattractant protein-1 (MCP-1), and IL-8 [10, 56, 57] which can inhibit preadipocyte differentiation [21, 45]