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Oxalates: What Your Genes and Diet Say About Oxalate Health Issues
Additionally, the use of piperlongumine (PLN) has been found to disrupt redox homeostasis, thereby increasing the sensitivity of cancer cells to MTH1 inhibitors
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Innate immune regulators, including the NLRP3 inflammasome, toll-like receptors (TLRs), and interferon pathways, have become priority targets for reducing chronic vascular inflammation and stabilizing high-risk plaques (Kong et al., 2022) Selective cytokine-targeted therapies, such as inhibitors of IL-1β, IL-6, and granulocyte–macrophage colony-stimulating factor (GM-CSF), are under investigation to suppress specific inflammatory pathways with fewer systemic adverse effects than broad immunosuppressive agents (Narazaki and Kishimoto, 2022